Citing NC-Scorer

If you use NC-Scorer or the Nephro Candidate Score (N-CS) framework in your research, please cite both the primary research publication and the software release.

Primary Research Publication

The methodology, machine learning models (N-GS and N-VS), and clinical validation of the Nephro Candidate Score framework are described in:

Rank N, Lukassen S, Anderegg MA, Eckardt KU, Halbritter JP, Popp B.
Automatic variant prioritization in suspected genetic kidney disease using the Nephro Candidate Score (N-CS).
medRxiv 2025.
DOI: 10.1101/2025.09.29.25336840

BibTeX

@article{rank2025nephro,
  author    = {Rank, Nina and Lukassen, S{\"o}ren and Anderegg, Manuel A. and Eckardt, Kai-Uwe and Halbritter, Jan P. and Popp, Bernt},
  title     = {Automatic variant prioritization in suspected genetic kidney disease using the Nephro Candidate Score (N-CS)},
  journal   = {medRxiv},
  year      = {2025},
  doi       = {10.1101/2025.09.29.25336840},
  url       = {https://doi.org/10.1101/2025.09.29.25336840},
  publisher = {Cold Spring Harbor Laboratory Press}
}

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Software Archive & Versioned Tool

To cite the specific version of the NC-Scorer web application used for data analysis and scoring:

Rank N, Lukassen S, Anderegg MA, Eckardt KU, Halbritter JP, Popp B.
NC-Scorer: Nephro Candidate Score Web Application and Framework (v3.7.0).
GitHub Release / Zenodo.
Release Tag: v3.7.0
URL: https://nc-scorer.kidney-genetics.org/

BibTeX

@software{nc_scorer_v3_7_0,
  author       = {Rank, Nina and Lukassen, S{\"o}ren and Anderegg, Manuel A. and Eckardt, Kai-Uwe and Halbritter, Jan P. and Popp, Bernt},
  title        = {NC-Scorer: Automated Variant Prioritization in Suspected Genetic Kidney Disease},
  version      = {v3.7.0},
  year         = {2026},
  howpublished = {\url{https://github.com/halbritter-lab/nc-scorer/releases/tag/v3.7.0}},
  url          = {https://nc-scorer.kidney-genetics.org/},
  publisher    = {GitHub / Zenodo},
  license      = {MIT}
}

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GitHub "Cite this repository"

Machine-readable citation metadata is provided in CITATION.cff according to the Citation File Format (CFF 1.2.0) specification.

On the GitHub repository page, click the "Cite this repository" button in the right sidebar to:

• Copy formatted APA citation
• Export formatted BibTeX entry
• Access both the software citation and preferred preprint article citation

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Related Repositories

The complete N-CS computational ecosystem includes:

• Web Tool & Frontend: halbritter-lab/nc-scorer — Vue 3 web interface and batch processing engine.
• Machine Learning & Preprocessing: halbritter-lab/nephro_candidate_score — N-GS feature extraction (R) and N-VS model training (Python).
• Kidney Genetics Evidence: halbritter-lab/kidney-genetics-v1 — Underlying curated gene-disease relationships.